王锐，男，汉族。第十四届全国政协常委，中国工程院院士（医药卫生学部），中国医学科学院学术咨询委员会学部委员，中国医学科学院药物研究所执行所长，亚洲通网址,亚洲通：特聘教授，兰州大学萃英学者一级教授，中国药学会副理事长，中华医学会常务理事，国家药典委员会执行委员，教育部“多肽药物”创新团队负责人，教育部长江学者特聘教授，国家万人计划领军人才，国家杰出青年科学基金获得者。1978年考入兰州大学，1988年获博士学位（兰州大学与日本京都大学联合培养），兰州大学博士后，美国University of Kansas博士后，香港理工大学教授。曾任兰州大学副校长、医学部主任、基础医学院院长、生命科学学院创院院长、甘肃省科协副主席，第十二届全国政协委员、第十三届全国政协常委。
      院校引进人才，2021年加入院校。

王锐院士率领团队长期围绕制约多肽新药创制的关键科学和技术问题，进行了系统的创新性研究，取得了突出成就，为我国多肽新药创制及产业化的发展做出了重要贡献。作为第一完成人获国家自然科学奖二等奖和国家技术发明奖二等奖各1项、教育部科技一等奖2项、甘肃省科技一等奖2项、国际学术奖励3项、获何梁何利科技奖。以通讯作者发表SCI论文500余篇，论文被引用2万余次，连续九年入选Elsevier“中国高被引学者”。获国家发明专利授权和美国、欧盟及日本授权发明专利80余件，多项专利技术用于多肽新药研发与生产，获中国专利奖。通过产学研合作研发的若干创新药正在进行临床试验。为我国培养了一大批德才兼备的优秀人才。

亚洲通网址,亚洲通

1．Kun Wang#，Ke Wang#，Cong Wang，Hange Yang，Gangzhong Zhou，Peihong Ji，Xudong Sun，Gong Chen，Xuegong Fan，Kuan Hu*，Juan Yi*, Hailong Zhang* and Rui Wang*. Development of Dual-Receptor Lysosome-Targeting Chimeras for Protein Degradation. Journal of the American Chemical Society. 2025. https://doi.org/10.1021/jacs.5c13695. (IF=15.6).

2．Kun Wang#, Cong Wang#, Hange Yang#, Gong Chen#, Ke Wang, Peihong Ji, Xudong Sun, Xuegong Fan, Jie Ma, Zhencun Cui, Xingkai Wang, Hao Tian, Dengfu Wu, Lu Wang, Zhimin Wang, Jiangyan Liu, Juan Yi*, Kuan Hu*, Hailong Zhang*, Rui Wang*. A dual-targeting peptide–drug conjugate based on CXCR4 and FOLR1 inhibits triple-negative breast cancer. Acta Pharmaceutica Sinica B. 2025. 15 (10): 4995-5009 (IF=14.6).

3．Ruixuan Wang#, Siqi Ran#, Jiabei Guo#, Da Hu#, Xiang Feng, Jixia zhou, Zhanzhi Zhang, Futian Liang, Jiamin Shang, Lingxin Bu, Kaiyi Wang, Junyi Mao, Huixin Luo*, Rui Wang*. mRNA display-enabled discovery of proximity-triggered covalent peptide–drug conjugates. Acta Pharmaceutica Sinica B. 2025. 15 (10): 5474-5485 (IF=14.6).

4．Quan Zuo#, Xinyi Song#, Jie Yan#, Guangjun Bao, Yiping Li, Jieting Shen, Zeyuan He, Kuan Hu*, Wangsheng Sun*, Rui Wang*. Triazination/IEDDA Cascade Modular Strategy Installing Pyridines/Pyrimidines onto Tyrosine Enables Peptide Screening and Optimization. Journal of the American Chemical Society. 2025. 147 (11): 9576–9589 (IF=15.6).

5．Siqi Zhang, Xingkai Wang, Xin Gao, Xueyao Chen, Linger Li, Guoqing Li, Can Liu, Yuan Miao, Rui Wang*, Kuan Hu*. Radiopharmaceuticals and their applications in medicine. Signal Transduction and Targeted Therapy. 2025. 10, 1. (IF=52.7).

6．Zhen Shan, Jian-Ze Xiao, Miaomiao Wu, Jinjian Wang, Jian Su, Ming-Shui Yao*, Ming Lu, Rui Wang*, Gen Zhang*. Topologically Tunable Conjugated Metal–Organic Frameworks for Modulating Conductivity and Chemiresistive Properties for NH3 Sensing. Angewandte Chemie-International Edition. 2024. 63 (16): e202401679 (IF=16.9).

7．Quan Zuo, Yiping Li, Xuanliang Lai, Guangjun Bao, Lu Chen, Zeyuan He, Xinyi Song, Ruiyao E, Pengxin Wang, Yuntao Shi, Huixin Luo, Wangsheng Sun*, Rui Wang*. Cysteine-specific Multifaceted Bioconjugation of Peptides and Proteins Using 5-Substituted 1,2,3-Triazines. Advanced Science. 2024. 11 (21): 2308491 (IF=15.1).

8．Guangjun Bao, Xinyi Song, Yiping Li, Zeyuan He, Quan Zuo, Ruiyao E, Tingli Yu, Kai Li, Junqiu Xie*, Wangsheng Sun*, Rui Wang*. Orthogonal bioconjugation targeting cysteine-containing peptides and proteins using alkyl thianthrenium salts. Nature Communications. 2024. 15, 6909 (IF=15.7).

9．Hange Yang*, Xiaowei Zhang*, Cong Wang*, Hailong Zhang*#, Juan Yi, Kun Wang, Yanzhe Hou, Peihong Ji, Xiaojie Jin, Chenghao Li, Min Zhang, Shan Huang, Haoyuan Jia, Kuan Hu, Lingyun Mou*, Rui Wang*. Microcolin H, a novel autophagy inducer, exerts potent antitumour activity by targeting PITPα/β. Signal Transduction and Targeted Therapy. 2023. 8(1):428 (IF=40.8).

10．Tongtong Liu, Yayun Zhang, Zhen Shan, Miaomiao Wu, Bocong Li, Hao Sun, Guanyong Su*, Rui Wang*, Gen Zhang*. Covalent organic framework membrane for efficient removal of emerging trace organic contaminants from water. Nature Water. 2023. 1, 1059–1067 (IF=20.1).