Toshio Suda，研究员，中国医学科学院亚洲通网址,亚洲通：特聘教授，博士研究生导师。曾获得美国血液学年会（ASH）E. Donnall Thomas Lecture and Prize，获国家海外引进高层次领军人才称号。曾任国际实验血液学学会的主席，现任其会刊Exp Hematol的主编，众多国际学术期刊编辑委员会委员。获得国家自然科学基金国际合作，中国医学科学院医学与健康创新工程医学健康领军科技人才等项目资助。
      院校引进人才，2024年加入院校，曾在新加坡国立大学癌症研究所任高级首席研究员。

长期从事造血干细胞调控及癌症代谢调控的研究。过往研究工作涵盖了造血干细胞的纯化、造血过程中细胞因子信号传导的识别，以及骨髓中造血干细胞微环境的特征描述。确定了造血干细胞的骨内膜微环境（《细胞》，2004 年），开创了氧化应激与干细胞衰老这一全新研究领域（《自然》，2004 年；《自然医学》，2006 年）。目标是将团队的研究成果转化到临床应用中，开发针对干细胞微环境的癌症疗法，为干细胞移植以及血液系统疾病的治疗做出贡献。

亚洲通网址,亚洲通

1．Haruhito Totani # , Takayoshi Matsumura # , Rui Yokomori , Terumasa Umemoto, Yuji Takihara , Chong Yang , Lee Hui Chua , Atsushi Watanabe , Takaomi Sanda , Toshio Suda*. Mitochondria-enriched hematopoietic stem cells exhibit elevated self-renewal capabilities, thriving within the context of aged bone marrow. Nat Aging. 2025 May;5(5):831-847. (IF=27.5)

2．Tomomasa Yokomizo #, Takako Ideue , Saori Morino-Koga , Cheng Yong Tham , Tomohiko Sato , Naoki Takeda , Yoshiaki Kubota , Mineo Kurokawa , Norio Komatsu , Minetaro Ogawa , Kimi Araki , Motomi Osato , Toshio Suda*. Independent origins of fetal liver haematopoietic stem and progenitor cells. Nature. 2022 Sep;609(7928):779-784.  (IF=64.8)

3．Chong Yang#, Rui Yokomori , Lee Hui Chua , Shi Hao Tan , Darren Qiancheng Tan , Kenichi Miharada , Takaomi Sanda , Toshio Suda*. itochondria transfer mediates stress erythropoiesis by altering the bioenergetic profiles of early erythroblasts through CD47. J Exp Med. 2022 Dec 5;219(12):e20220685. (IF=17.6)

4．Kentaro Hosokawa #, Ben D MacArthur , Yoshiko Matsumoto Ikushima , Hirofumi Toyama , Yoshikazu Masuhiro5, Shigemasa Hanazawa*, Toshio Suda *, Fumio Arai*.  Nat Commun. 2017 Oct 6;8(1):804. (IF=12.1)

5．Masayuki Yamashita #, Eriko Nitta, Toshio Suda*. Aspp1 Preserves Hematopoietic Stem Cell Pool Integrity and Prevents Malignant Transformation. Cell Stem Cell. 2015 Jul 2;17(1):23-34. (IF=25.3)

6．Kana Miyamoto #, Kiyomi Y Araki #, Kazuhito Naka , Fumio Arai , Keiyo Takubo , Satoshi Yamazaki , Sahoko Matsuoka , Takeshi Miyamoto , Keisuke Ito , Masako Ohmura , Chen Chen , Kentaro Hosokawa , Hiromitsu Nakauchi , Keiko Nakayama , Keiichi I Nakayama , Mine Harada, Noboru Motoyama* , Toshio Suda *, Atsushi Hirao*. Foxo3a is essential for maintenance of the hematopoietic stem cell pool. Cell Stem Cell. 2007 Jun 7;1(1):101-112. (IF=23.4)

7．Keisuke Ito#, Atsushi Hirao #, Fumio Arai, Keiyo Takubo, Sahoko Matsuoka, Kana Miyamoto, Masako Ohmura, Kazuhito Naka, Kentaro Hosokawa, Yasuo Ikeda, Toshio Suda*. Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat Med. 2006 Apr;12(4):446-51. (IF=28.0)

8．Keisuke Ito #, Atsushi Hirao#, Fumio Arai, Sahoko Matsuoka, Keiyo Takubo, Isao Hamaguchi, Kana Nomiyama, Kentaro Hosokawa, Kazuhiro Sakurada, Naomi Nakagata, Yasuo Ikeda, Tak W Mak, Toshio Suda*. Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells. Nature.  2004 Oct 21;431(7011):997-1002. (IF=32.3)

9．Fumio Arai #, Atsushi Hirao, Masako Ohmura, Hidetaka Sato, Sahoko Matsuoka, Keiyo Takubo, Keisuke Ito, Gou Young Koh, Toshio Suda*. Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell. 2004 Jul 23;118(2):149-61. (IF=28.4)

10．N Takakura #, T Watanabe, S Suenobu, Y Yamada, T Noda, Y Ito, M Satake, T Suda*. A role for hematopoietic stem cells in promoting angiogenesis. Cell. 2000 Jul 21;102(2):199-209. (IF=29.4)