王艳，1982年生，分子肿瘤学国家重点实验室研究员，博士生导师。2009年毕业于北京大学，获生物化学与分子生物学博士学位。曾获国家自然科学二等奖（第二完成人）。获得国家杰出青年科学基金、国家优秀青年科学基金资助。入选国家级青年人才项目、创新人才推进计划“中青年科技领军人才”、百千万人才工程国家级人选。
      院校引进人才。曾在山东大学医学院任副教授，天津医科大学和首都医科大学任教授。2019年10月进入中国医学医学院肿瘤医院任研究员。

肿瘤发生发展与转移的表观遗传转录调控机制；肿瘤代谢微环境通过表观遗传重编程促癌的分子机理，主要研究生活方式、环境毒素和药物治疗对肿瘤代谢微环境及表观重编程的影响和具体机制。

亚洲通网址,亚洲通

1. Dandan Feng#, Jie Gao#, Ruiqiong Liu#, Wei Liu, Tianyang Gao, Yunkai Yang, Die Zhang, Tianshu Yang, Xin Yin, Hefen Yu, Wei Huang*, Yan Wang*. CARM1 drives triple-negative breast cancer progression by coordinating with HIF1A. Protein Cell 2024; 15(10): 744-765. (IF= 12.7998)

2. Tianshu Yang, Wei Huang, Tianyu Ma, Xin Yin, Jingyao Zhang, Miaomiao Huo, Ting Hu, Tianyang Gao, Wei Liu, Die Zhang, Hefen Yu, Xu Teng, Min Zhang, Hao Qin, Yunkai Yang, Baowen Yuan, Yan Wang*. The PRMT6/PARP1/CRL4B Complex Regulates the Circadian Clock and Promotes Breast Tumorigenesis, Advanced Science 2023; 10(14):e2202737. (IF= 14.2994)

3. Wei Liu#, Yi Zeng#, Xinhui Hao, Xin Wang, Jiaxiang Liu Tianyang Gao, Mengdi Wang, Jingyao Zhang, Miaomiao Huo, Ting Hu, Tianyu Ma, Die Zhang, Xu Teng, Hefen Yu, Min Zhang, Baowen Yuan, Wei Huang*, Yunkai Yang*, Yan Wang*. JARID2 coordinates with the NuRD complex to facilitate breast tumorigenesis through response to adipocyte-derived leptin, Cancer Communications 2023; 43(10): 1117-1142. (IF= 20.0992)

4. Xin Yin, Xu Teng, Tianyu Ma, Tianshu Yang, Jingyao Zhang, Miaomiao Huo, Wei Liu, Yunkai Yang, Baowen Yuan, Hefen Yu, Wei Huang*, Yan Wang*. RUNX2 recruits the NuRD(MTA1)/CRL4B complex to promote breast cancer progression and bone metastasis. Cell Death & Differentiation 2022; 29(11):2203-2217. (IF= 12.4002).

5. Wei Huang, Jingyao Zhang, Miaomiao Huo, Jie Gao, Tianshu Yang, Xin Yin, Pei Wang, Shuai Leng, Dandan Feng, Yang Chen, Yang Yang, Yan Wang*. CUL4B Promotes Breast Carcinogenesis by Coordinating with Transcriptional Repressor Complexes in Response to Hypoxia Signaling Pathway. Advanced Science 2021; 8(10): 2001515. (IF=17.5213)

6. Shuai Leng, Wei Huang, Yang Chen, Yang Yang, Dandan Feng, Wei Liu, Tianyang Gao, Yanli Ren, Miaomiao Huo, Jingyao Zhang, Yunkai Yang, Yan Wang*. SIRT1 Coordinates with the CRL4B Complex to Regulate Pancreatic Cancer Stem Cells to Promote Tumorigenesis. Cell Death & Differentiation 2021; 28(12): 3329-3343. (IF= 12.0736)

7. Yongqiang Hou, Wei Liu, Xianfu Yi, Yang Yang, Dongxue Su, Wei Huang, Hefen Yu, Xu Teng, Ying Yang, Wei Feng, Tao Zhang, Jie Gao, Kai Zhang, Rongfang Qiu, Yan Wang*. PHF20L1 as a Novel H3K27me2 Reader Coordinates with Transcriptional Repressors to Promote Breast Tumorigenesis. Science Advances 2020; 6(16), eaaz0356. (IF=14.136)

8. Wenzhe Si, Wei Huang, Yu Zheng, Yang Yang, Xujun Liu, Lin Shan, Xing Zhou, Yue Wang, Dongxue Su, Jie Gao, Ruorong Yan, Xiao Han, Wanjin Li, Lin He, Lei Shi, Chenghao Xuan, Jing Liang, Luyang Sun, Yan Wang*, Yongfeng Shang*. Dysfunction of the Reciprocal Feedback Loop between GATA3- and ZEB2- Nucleated Repression Programs Contributes to Breast Cancer Metastasis. Cancer Cell 2015; 27(6): 822-36. (IF=23.214)

9. Huili Hu, Yang Yang, Qinghong Ji, Wei Zhao, Baichun Jiang, Ruiqiong Liu, Jupeng Yuan, Qiao Liu, Xi Li, Yongxin Zou, Changshun Shao, Yongfeng Shang, Yan Wang*, Yaoqin Gong*. CRL4B Catalyzes H2AK119 Monoubiquitination and Coordinates with PRC2 to Promote Tumorigenesis. Cancer Cell 2012; 22(6): 781-95. (IF=24.755)

10. Yan Wang, Hua Zhang, Yupeng Chen, Yimin Sun, Fen Yang, Wenhua Yu, Jing Liang, Luyang Sun, Xiaohan Yang, Lei Shi, Ruifang Li, Yanyan Li, Yu Zhang, Qian Li, Xia Yi, and Yongfeng Shang*. LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer. Cell 2009; 138(4): 660-72. (IF=31.152, C100)